GENOMICS PLATFORM(CAPE TOWN OFFICE)The South African Medical Research Council (SAMRC) strives to improve the nation’s health and quality of life by funding and conducting relevant and leading health research. It further aims to promote equity, career development and progression.SENIOR SCIENTIST (C)Duration: One Year ContractThe SAMRC’s Genomics Platform in collaboration with Environment & Health Research Unit requires a Senior Scientist to carry out data science related activities required for model training, testing and validation. The incumbent will also support the piloting of the two applications of large language models (LLMs) applied to variant emergence/detection, including work such as merging datasets to fine-tune both LLMs against raw metagenome sequence data. The aim of this study is to establish a proof of concept for the integration of wastewater surveillance, metagenomics and artificial intelligence (AI) in disease detection, particularly focusing on its application in the South African context.Responsibilities:Publishing articles in peer reviewed journalsSubstantially contribute to drafting of research proposals.Project Management which will include coordination of projects: Developing of research tool and SOPs/techniquesOrganization and management of DataQuality assurance and ensure adherence to SOPsConduct data analysis and write-upEngage with stakeholdersResearch translationWork in Linux environments.Scripting in Python, C#, Java and R.Processing and Analysis of Next Generation sequencing data.Co-/Supervision of 1 master’s student or 5 hours engagement in teaching or training (may be of staff in the Unit) including capacity building of staff, training and technical support provided Poster or oral presentations at local or international conferences or at external meetings where own research is presentedBuilding bioinformatics networks – both local and international.Core Requirements:Master’s degree in molecular biology, Genetics or a related field. At least 2 years research experience in computational and statistical analysis of high-dimensional and multivariate data At least 2 years’ experience in Project management and data management Presenting research findings and reports at relevant conferences/meetings Familiar and up-to-date knowledge of next generation sequencing modalities Experience in working in Linux environments. Proficiency in common scripting languages (Python, Java and R) At least 1 year with next generation sequencing data analysisAdvantageous:Registered for a PhD in molecular biology, Human Genetics of a related field.Experience with Good Clinical/Laboratory Practices. A track record initiation and management of several research projects. Comprehensive use of computational clusters for all analytical methods. Knowledge of Large Language Models.Terms & Conditions: The SAMRC retains the right not to make an appointment. In accordance with the SAMRC’s Employment Equity Plan, preference will be given to suitably qualified candidates from the designated groups. For this reason, we require race, gender and disability status to be specified. Disabled persons are encouraged to apply. By submitting your application, SAMRC concludes that you are a competent person to consent and that you are giving consent to the SAMRC to process and further process all personal information contained in the application in accordance with the Protection of Personal Information Act, Act No 4 of 2013 (as amended). The SAMRC does its best to provide the most accurate information; however, if there is anything wrong and unclear applicants are encouraged to contact the HR Recruitment Office at 021-938 0648 before the closing date.A salary in the region of R779 666 per annum, cost-to-company will be negotiated in accordance with qualifications and experience.Closing date: 25 June 2024PLEASE QUOTE THE REFERENCE NUMBER (R737A) IN ALL COMMUNICATIONS. PLEASE BE ADVISED THAT YOUR SUBMISSION WILL NOT BE CONSIDERED SHOULD YOUR APPLICATION NOT BE ACCOMPANIED BY THE REQUIRED INFORMATION AND DOCUMENTATION.This website is optimised for secure, standards compliant web browsers. In order to view and use this website, you should use a web browser other than Internet Explorer.Options include: The latest version of 'Chrome, Microsoft Edge, Firefox, Opera and Safari'#J-18808-Ljbffr